BioBIKE: Principles (cont)
- Interconvert between gene and protein as appropriate
Those functions that require proteins will convert genes to proteins
and those functions that require genes will do the opposite.
Examples:
BioBIKE code
(GENE-UPSTREAM-OF (ORTHOLOG-OF p-NpF0001 IN A7120 CUTOFF 1e-6))
Finds gene upstream of the gene encoding the protein ortholog in Anabaena
(MW-OF (GENE-UPSTREAM-OF NpF0001))
Gives the molecular weight of the protein encoded by the upstream gene
BioBIKE code giving equivalent results
(GENE-UPSTREAM-FROM
(SLOTV (TWO-WAY-ORTHOLOG-OF #$Npun.NpF0001 PCC7120 1e-6) #$Gene))
(MOLECULAR-WEIGHT-OF
(EXTRACT-SEQUENCE
(FIRST (SLOTV (GENE-UPSTREAM-FROM #$Npun.NpF0001) #$PROTEINS))))
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