VCU Bioinformatics and Bioengineering Summer Institute
Virginia Commonwealth University

Hoda Khouri

Presentation Thursday July 10, 2003

Bacterial Genome Finishing at TIGR

§        Shotgun sequencing

§        Steps in closure or finishing

§        Multiplex PCR

§        S. pneumoniae closure and annotation

§        Comparison of Strep. Strains

§       TIGR software for sequence comparison and repeat handling

 

The life and times

Education

§        BS, MS: American University of Beirut in Lebanon

§        Agriculture/ Animal science

Work Experience

§        Animal Virology

      cell culture and growing different viruses

      American University of Beirut

§       Autoimmune Disease

      1985 – University of Massachusetts

      a model of human Vitiligo that affects chicken

§        Toxicology Lab

      1989 – Reston, VA

      developed an interest in molecular biology

§        Animal Virologist

      ATCC (American Type Culture Collection)

      collection and authentication

TIGR
      
The Institute for Genomics Research

§        1998 to present

§        Molecular Biologist

§        Gap Closure Team Leader

      Supervises 14 Molecular Biologists

      Currently working with 11 genomes (1-25Mb)

      Successfully closed 3 Streptococcus genomes